Due to my having a variant GI system (with its own side-effects), my oncologist, in an abundance of caution, started me on Imbruvica 1 capsule in the AM, daily. Literally within days, the SIGNIFICANTLY large lymphs in the front and rear of my neck, disappeared. WOW! Cost of Ibrutinib in Usa MY WBC's skyrocketed, but that is typically expected due to the mechanisms by which Imbruvica works. Oversimplifying here -- the abnormal (cancerous) cells, congregate in the lymphs. Imbruvica forces those abnormal cells out into the bloodstream, where they can be attacked and starved of the BTK protein, which they need to thrive and propagate. The "dead" abnormal cells are then flushed out of the body. After 2 months dose upped to 2 capsules daily, and still tolerating well. Heptopic! caring with quality curing, we are providing Anti-Cancer drugs (generic brand) for breast cancer, lung cancer, blood cancer & other cancer medicine at affordable prices all over world.Ibrutinib Cost’s makers, Janssen and Pharmacyclics, have now gotten approval to sell four different tablets of varying strengths: 140mg, 280mg, 420mg, and 560mg. But the new pills will all be the same price—around $400 each—even the 140mg dose pill. The makers will stop selling the old, cheaper 140mg pill within three months, according to a report by the Washington Post.The plan nixes any chance to lower costs with lower dosages. Even if patients can drop down to just 140mg a day, they’ll pay three times what they pay now for each 140mg pill.In a statement to the Post, Janssen and Pharmacyclics explained the move by saying the new line-up is “a new innovation to provide patients with a convenient one pill, once-a-day dosing regimen and improved packaging, with the intent to improve adherence to this important therapy.” They noted that those taking 560mg a day will save money with the new pricing.But doctors balked at what they saw as an underhanded move. In an interview with the Post, oncologist Mark Ratain of the University of Chicago Medicine put things bluntly: “That got us kind of pissed off.”Ratain and colleagues wrote a commentary in the weekly newsletter Cancer Letters this month, decrying the price hike and new pill series, calling it “highly unusual.” In addition to thwarting efforts to help lower treatment costs, the doctors pointed out that the new dosage lineup will make it harder to nimbly adjust patients’ doses by simply advising them to take different numbers of pills each day. Switching a patient from a 280mg or 420mg per day dose down to 140mg will require paperwork, filling a new prescription, and having patients return unused pills—a process that can drag out for weeks. And increasing a patient’s dose would either be just as lengthy of a process or risk multiplying their treatment costs even further by doubling or tripling the pills each day.
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